Coupling-isomerization-Claisen sequences - mechanistic dichotomies in hetero domino reactions.
نویسندگان
چکیده
A new coupling-isomerization-Claisen domino reaction starting from electron deficient halides and 1-(hetero)aryl propargyl trityl ethers dichotomizes in the concluding steps of the sequence and gives rise to the formation of tricyclo[3.2.1.0(2,7)]oct-3-enes, enones, 1H-isochromenes, or indans as a consequence of minute differences of substituent effects.
منابع مشابه
Dichotomies in microwave-assisted propargyl-isomerization-Claisen domino sequences dependent on base strengths.
Microwave-assisted unimolecular isomerization-Claisen domino reactions of 1,3-di(hetero)aryl propargyl trityl ethers lead, depending on the basicity of the amine, either to the formation of tricyclo[3.2.1.0(2,7)]oct-3-enes (with triethylamine) or to indanes (with DBU). Based upon product analyses and computations, this base dependent dichotomy can be rationalized as a sequel of pericyclic react...
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ورودعنوان ژورنال:
- Chemical communications
دوره 39 شماره
صفحات -
تاریخ انتشار 2006